With the release of his film "Head On" to look forward to, Vincent Chase is a star on the rise. To help him adjust to life in L.A., he's brought his best pals Eric and Turtle with him from Queens and put them on his payroll, along with his actor brother Johnny Drama. The reviews for the movie aren't great, but "Head On" opens big and the critics single out Vince as the "next Johnny Depp".
Flush with success, the boys enjoy life in the fast lane and access to girls, parties and quality weed. As Vince's closest friend, and now manager, Eric has the responsibility of giving scripts a thumbs up or down, a role that often puts him in conflict with Ari, Vince's more experienced, pit bull of an agent. When he reads "Queens Boulevard", a sure fire indie hit for Vince, Eric wants to put the wheels in motion for that project – even if Ari won't.